FAQ (frequently asked questions)

Why stem cells? Pfeil
Why stem cells?

Stem cells are the primordial soup from which all life originates. Their future forms have not been predetermined and they can be programmed by surrounding tissue to become any other kind of cell: into heart tissue, into spinal cord nerve cells, and in the future, even into whole organs. Without any chances of rejection whatsoever! Because there is nothing more readily accepted by the body than its own cells.

How is it done? Pfeil
How is it done?

A piece of skin, the size of a small coin, is removed using a quick surgical procedure, performed on an outpatient basis. Advanced cryotechnology is used to freeze the tissue, which is then stored in a kind of "Bio-Safe" under carefully controlled conditions. For as long as you'd like. Until you need it.

Why should I store stem cells now? Pfeil
Why should I store stem cells now?

Our genes carry instructions about how the organism is built and how metabolic processes should proceed. Genetic material, however, is constantly exposed to environmental influences that can lead to changes and mutations. Our bodies are constantly fighting influences such as radiation from the earth and sun, environmental toxins, and viral infections.

Why stem cells from the skin? Pfeil
Why stem cells from the skin?

Skin derived stem cells are pluripotent and may differentiate to all other tissues of the adult organism. They rejuvenate or repair organs by replacing defective cells. Today, pluripotency could only be shown for skin derived stem cells. Stem cells from other sources such as blood or bone marrow have not been proven to be pluripotent yet. Because of that, the skin is the ideal source for stem cells to ensure a life in health.

When is the best time to store stem cells? Pfeil
When is the best time to store stem cells?

Stem cells age too and can change due to environmental influences. In addition, the organism can be systematically affected by cancer, so that healthy cells - those without impurities - can no longer be isolated. Therefore, the most prudent advice is: the earlier a piece of skin tissue can be extracted and preserved, the better off you are. But better late than never! It's like setting aside a piece of your youth for later.

What's in it for me? Pfeil
What's in it for me?

The security of knowing you can take advantage of innovate medical procedures in the near future. And then - when you need healthy adult stem cells for diagnostic or therapeutic purposes - of having the stem cells at your instant disposal.

Who can store tissue with TICEBA? Pfeil
Who can store tissue with TICEBA?

Anyone can store a piece of skin tissue, and the stem cells contained therein, with us.

Aren't I too old for storing stem cells? Pfeil
Aren't I too old for storing stem cells?

Stem cells can be obtained from skin tissue even in very advanced age, to be used for future medical needs and applications. Once again: the earlier the better, but better late than never!

Who has access to the stored cells? Pfeil
Who has access to the stored cells?

Only you personally, have access to the tissue sample, and only you can determine when and how the stem cells in the sample are used.

How long can my cells be stored? Pfeil
How long can my cells be stored?

The cells can be preserved for future medical needs and applications for at least 20 years.

News
Coronavirus and Mesenchymal Stem Cells

Therapy for Pneumonia Patients iInfected by 2019 Novel Coronavirus

Treatment With Mesenchymal Stem Cells for Severe Corona Virus Disease 2019(COVID-19)

Mesenchymal Stem Cell Treatment for Pneumonia Patients Infected With 2019 Novel Coronavirus

Article about our study with limbal stem cells

On the website of the Harvard Stem Cell Institute you will find the following news release about the ongoing clinical trial conducted by our daughter company RHEACELL in patients suffering from limbal stem cell deficiency: Restoring vision: A stem cell therapy for cornea regeneration reaches the clinical-trial stage.

Clinical Trial - EB

The international phase I/IIa clinical trial has been approved by the U.S. Food and Drug Administration (FDA) and several European competent national regulatory authorities. The medicinal drug product tested in this trial has recently been granted Orphan Drug designation from the FDA and the European Medicines Agency (EMA) for the treatment of EB.

Clinical Trial - LSCD

The international phase I/IIa clinical trial has been approved by the U.S. Food and Drug Administration (FDA) and the German regulatory authority (Paul Ehrlich Institute). The medicinal drug product tested in this trial has recently been granted Orphan Drug designation from the FDA and the European Medicines Agency (EMA) and Fast Track designation from the FDA for the treatment of LSCD.

Safety

In a comprehensive preclinical study program, safety and local tolerability of ABCB5+ MSCs following subcutaneous, intramuscular and intravenous application has been demonstrated (Tappenbeck et al., 2019).

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